Stress and Rest SPET introduction - Nuclear Medicine InfoSite

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NUCLEAR CARDIOLOGY

The nuclear cardiology (amidst the main application areas always in relation to the radiopharmacological chosen) allows the displaying of the state of the heart muscle by blood flow, mitochondrial density content, vitality, contractility parameters, and recently innervation.  It can allow stress-study and comparison with the resting-state study, by means of 3D regeneration of the signal emitted (called "radioactivity") after the injection.  The main methods used are the SPET and PET, realized in various ways, even with the heart rate synchronization (Gated-SPET or Gated-PET depending on the indications and instrument availability).  

SPET and SPECT are synonyms for Gamma-Cameras instruments with TOMO (3D) acquisition and reconstruction capabilities of the scan range.  The primary signal considered is the one emitted by the radiopharmaceutical given.  It has been some years since the newest SPET/CT hybrid versions have been developed, with the same principles as the most advanced PET testing, but with the ability to improve the most traditional nuclear medicine approach, which still uses so-called “single photon emission” radiopharmaceuticals, not "dual photon emission" and opposed by direction at the same time as that emitted by positron-emitters drugs.

A widespread option is the synchronized SPET reconstruction with the (Gated) ECG trace, indispensable for calculating the left ventricular kinetics parameters with functional indicators of cardiac muscle pump capacity, particularly the left ventricle.
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